WebApr 17, 2015 · To better characterize which hematopoi-etic cells contain hCD2-iCre activity, we compared EYFP fluorescence in hCD2-iCre +/ Murine CD2 mRNA tissue expression … Webet al., 2006) with the CLP cells specific CRE line hCD2-iCRE (de Boer et al., 1988) and generated a cohort of POT1aF/FhCD2Cre (hereafter referred to as POT1Cd2) mice. The resulting mice were viable, but displayed a marked reduction in circulating mature B and T cells and fewer splenic B cells and
027406 - hCD2-cre Strain Details - The Jackson Laboratory
Webmice from each of the Cre-transgene expressing lines. Mice from the hCD2-Cre Snf5fl/fl line aged normally and were not cancer prone. In contrast, all mice from both the Lck-Cre Snf5fl/fl and CD4-Cre Snf5fl/fl Figure 1 Schematic of T cell development. CLP cells originate in the bone marrow and migrate to the thymus. Cells at the CD4–CD8– DN ... WebAtoh1 tm2.1(cre/ERT2,-CD2)Dwi: Name: atonal bHLH transcription factor 1; targeted mutation 2.1, Douglas J Winton: MGI ID: MGI:7444368: Synonyms: Atoh1 (9S/T-A)CreERT2: ... (9S/T-A) merged to the P2A-CreERT2-hCD2 then to a neomycin cassette inserted such that the 3'UTR was not disrupted. Following successful germline … hp graphic drivers for windows 10
Identification and Education Exceptional Children Course (HB 671)
Webthe use of hCD2-Cre did not cause derepression of CD4 coreceptor in dKO mature CD8+ T cells (Supplementary Fig. 1a), validating specific deletion in post-thymic T cells. To directly address the WebDec 28, 2011 · The Aicda-cre system efficiently monitors Aicda expression. The Aicda-cre transgenic mouse carries a 190-kb BAC DNA containing the entire Aicda locus .The Aicda coding region on the transgene was engineered to generate the human CD2 and Cre recombinase instead of AID; thus, current Aicda promoter activation can be visualized by … WebNov 18, 2011 · We postulated that miRNAs serve an essential role in orchestrating NK cell development and activation. To test this hypothesis, we combined lymphocyte-restricted hCD2-Cre transgenic, Rosa26-YFP-Cre-reporter, and Dicer1 ‘floxed' mice. In this model, 25–50% of Dicer1 wt/wt NK cells are YFP + marking expression of Cre. hp graphics language plotter document