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Siglec 10 antibody

WebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane protein that has four extracellular Ig-like domains, a transmembrane region, and a cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (2). WebRabbit SIGLEC10 Rabbit pAb (A20413), validaed in WB and tested in Human,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. …

Anti-SIGLEC10 Antibody Rabbit anti-Human Polyclonal ELISA,WB

WebSiglec-10 Fc (Mouse IgFc) at 10 μg ml was incubated with anti-Siglec-10 antibodies and the Siglec-10Fc/antibody complexes were incubated with tumor cell lines and then washed. … WebOur Anti-Siglec-10 Monoclonal Antibody Program CD24 can promote immune evasion through interaction with Siglec-10; Siglec-10 is highly expressed on tumor-associated … symmetric to origin https://davesadultplayhouse.com

Siglec-10 Antibody, anti-human, REAfinity™ - Miltenyi Biotec

WebMouse anti Human Siglec-10 antibody, clone 5G6 recognises human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and member of the Ig superfamily, … WebPRO940 antibody, SIGLEC-10 antibody, SLG2 antibody, Siglecg antibody, SIGLEC10 antibody, slg2 antibody, pro940 antibody, siglec-10 antibody, sialic acid binding Ig like … Like most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more thabo trust

Anti-SIGLEC10 Antibody Mouse anti-Human Monoclonal Flo LSBio

Category:Anti Human Siglec-10 Antibody, clone 5G6 Bio-Rad

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Siglec 10 antibody

SIGLEC10 Polyclonal Antibody, Biotin - Thermo Fisher Scientific

WebExpression of SIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use … WebSiglec-10 is a lectin that specifically binds α-2,3- or α-2,6-linked sialic acid. It is a member of the Ig-superfamily and is expressed in monocytes, eosinophils, B cells, and a subset of NK …

Siglec 10 antibody

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WebClone REA1048 recognizes the human siglec-10 antigen, also known as sialic acid-binding Ig-like lectin 10, which is a member of the CD33-related group of siglecs. The cytoplasmic … WebRabbit Polyclonal Anti-SIGLEC10 Antibody against Human sialic acid binding Ig-like lectin 10. Antibody validation: Validated for Immunohistochemistry and Western Blot. Support; …

WebThe amounts of HMGB1 associated with CD24Fc were determined by immunoblotting with anti-HMGB1 monoclonal antibody. The data shown are ... the CD24/Siglec-10 interaction has been ... WebSIGLEC10 antibody LS-C325111 is an unconjugated rabbit polyclonal antibody to human SIGLEC10 (aa667-695). Validated for ELISA and WB. Products. Research Areas. COVID-19. Resources. ... SIGLEC10 SIGLEC-10 Siglec-like gene 2 Siglec-like protein 2 PRO940 SLG2. See All SIGLEC10 Antibodies. Host. Rabbit.

WebSIGLEC10 antibody LS-C187565 is an unconjugated mouse monoclonal antibody to human SIGLEC10. Validated for Flow. Products. Research Areas. COVID-19. Resources. ... (NK) cells. Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic ... WebClone 5G6 recognizes the sialic acid-binding Ig-like lectin 10 (Siglec-10) antigen, a member of the CD33-related group of siglecs. The cytoplasmic tail of Siglec-10 contains four …

WebThe 5G6 monoclonal antibody specifically recognizes Sialic acid-binding Ig-like lectin 10 (Siglec-10). Siglec-10 is a type I transmembrane glycoprotein encoded by SIGLEC10 …

WebAK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). Preclinical studies have demonstrated that monotherapy treatment with a … symmetric to the y axisWebSiglec-G is the apparent ortholog of human Siglec-10 (4). The human Siglec-10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a 534 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 126 aa cytoplasmic domain. The ECD contains one Ig-like V‑type domain and four Ig-like C2-type domains ... thabo tsotetsi ageWebNov 29, 2024 · Summary. Siglec-9 is an immune checkpoint target and an immunoinhibitory receptor that can engage either sialic acid ligands or agonistic antibodies. Through Siglec … thabo twalaWebSIGLEC 10 antibody. Siglec G antibody. Siglec-like protein 2 antibody. SIGLEC10 antibody. Siglecg antibody. SLG2 antibody : Protein information supplied by UniProt . Accessories. … symmetric tubes find nWebMar 21, 2024 · SIGLEC10 (Sialic Acid Binding Ig Like Lectin 10) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated … symmetric top moleculesWebApr 10, 2024 · The Siglec-Fc protein, a fusion protein combining Siglec with the Fc part of a human antibody, is a promising sialic acid-Siglec axis-targeted agent for cancer treatment … thabo tsoariWeb1 day ago · Although the exact role of Siglec-1 in the context of HIV-1 infection is still an area of active ... more convenient antibody treatments. Apr 13, 2024. T cells: Vesicles strengthen immune response. symmetric tires